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KMID : 0356919960300060703
Korean Journal of Anesthesiology
1996 Volume.30 No. 6 p.703 ~ p.710
Effect of Augmented Minute Ventilation on Cardiovascular and Ventilatory Changes during the Laparoscopic Cholecystectomy under General Anesthesia



Abstract
Background:
@EN The pneumoperitoneum created byCO2 insufflation during laparoscopic cholecystectomy has several potential hemodynamic and respiratory consequences.
The purpose of this study is to investigate the effects of augmented minute ventilation on cardiovascular and ventilatory changes and to prevent hypercarbia due to CO2 insufflation during laparoscopic cholecystectomy.
@ES Methods:
@EN Thirty-six patients were divided into three groups according to the level of minute ventilation. The three groups were: control group C(minute ventilation 100ml/kg, respiratory rate 12 per minute), group R(MV 150ml/kg, RR is 18 per
minute)
and group V (MV 150ml/kg,tidal volume is 1.5 times as much as group C).
We repeatedly measured mean arterial pressure, pulse rate, arterial blood gas analysis and end tidal carbon dioxide and peak inspiratory airway pressure before CO2 insufflation, 15 and 30 minutes after CO2 insufflation and
15
minutes after CO2 deflation.
@ES Results:
@EN During CO2 insufflation MAP significantly increased but PR showed little changes in all three groups. PaCO2 and PETCO2 increased in group C, whereas in group R and V, they remained unchanged during CO2 insufflation. But the level of PaCO2 in
group V
decreased more than in the other two group after CO2 deflation, PIP in group IV increased 3 times as much as the control value.
@ES Conclusions:
@EN These results suggest that augmented minute ventilation in group R and V, prevented hypercarbia during CO2 insufflation and increasing the tidal volume in controlled ventilation was more effective than increasing respiratory rate after CO2
deflation. (Korean J Anesthesiol 1996; 30: 703~710)
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